Genicular Nerve Radiofrequency Denervation

Genicular nerve radiofrequency denervation (RFD), also known as genicular nerve ablation, is a highly effective, minimally invasive treatment for chronic knee pain. It is especially valuable for patients who suffer from osteoarthritis, degenerative joint disease, or persistent pain following total knee replacement. This procedure targets the genicular nerves—small sensory nerves located around the knee joint—using radiofrequency energy to interrupt the transmission of pain signals to the brain.

When knee pain becomes severe enough to limit mobility and conservative treatments like physical therapy, bracing, or injections no longer provide adequate relief, genicular nerve RFD offers a non-surgical option that can restore quality of life. It’s also an ideal solution for patients who are not candidates for knee surgery due to age, health conditions, or personal choice.

What Conditions Does Genicular Nerve RFD Treat?

This procedure is commonly used for:

Knee osteoarthritis – Chronic degeneration of the knee joint cartilage resulting in pain and stiffness
Post-surgical knee pain – Persistent discomfort after knee replacement surgery
Degenerative joint disease – Age-related changes in the knee joint causing inflammation and nerve irritation
Non-surgical knee pain – For individuals who are unable or unwilling to undergo joint replacement

For more information about these knee pain sources, visit our Conditions Treated section.

How the Procedure Works

Before undergoing RFD, patients typically undergo a genicular nerve block to confirm the nerves are the source of their pain. During this test, a local anesthetic is injected into the area surrounding the genicular nerves. If the block results in significant, though temporary, pain relief, the patient is considered a good candidate for RFD.

The radiofrequency ablation procedure itself is performed under fluoroscopic (X-ray) guidance. After numbing the skin, a thin needle is placed near each of the targeted genicular nerves. A specialized probe is inserted through the needle, and radiofrequency energy is applied to create a small lesion on each nerve. This lesion disables the nerve’s ability to send pain signals without affecting motor function or joint movement.

The entire process takes about 30–60 minutes and is performed on an outpatient basis. Patients typically return home the same day and can resume normal activity within a day or two.

What to Expect After Treatment

Some patients may feel mild soreness or swelling at the injection site, which typically resolves within a few days. Pain relief generally begins within one to three weeks, once the targeted nerves are fully disabled. The results can last anywhere from six months to over a year. The procedure can be safely repeated if the nerves regenerate and pain returns.

Benefits of Genicular Nerve Radiofrequency Denervation

Long-lasting knee pain relief without the need for surgery
No implants or prosthetics
Helps delay or avoid knee replacement in many cases
Performed under local anesthesia with minimal recovery time
Reduces reliance on medications, including opioids

Get Back on Your Feet with Ascent Pain

At Ascent Pain, we understand how frustrating chronic knee pain can be. Whether your pain is due to arthritis, injury, or a prior surgery, genicular nerve radiofrequency denervation may offer the long-term relief you need to stay active and independent.

Call Ascent Pain at (504) 249-7576 or fill out our online form to schedule your consultation and take the next step toward pain-free movement.